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1

Crystal structure of unlinked NS2B-NS3 protease from Zika virus

Zhang, Zhenzhen, Li, Yan, Loh, Ying Ru, Phoo, Wint Wint, Hung, Alvin W., Kang, CongBao, Luo, Dahai

Journal:

Year:

2016

Language:

english

File:

PDF, 1.28 MB

english, 2016

2

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopesâ7

GÃ¼tschow, Michael, Vanden Eynde, Jean Jacques, Jampilek, Josef, Kang, CongBao, Mangoni, Arduino A., Fossa, Paola, Karaman, Rafik, Trabocchi, Andrea, Scott, Peter J. H., Reynisson, JÃ³hannes, Rapposel

Journal:

Year:

2020

File:

PDF, 2.84 MB

2020

3

West Nile virus protease activity in detergent solutions and application for affinity tag removal

Huang, Qiwei, Li, Qingxin, Chen, Angela Shuyi, Kang, Congbao

Journal:

Analytical Biochemistry

Year:

2013

Language:

english

File:

PDF, 653 KB

english, 2013

4

Biophysical Studies of Bacterial Topoisomerases Substantiate Their Binding Modes to an Inhibitor

Kang, CongBao, Li, Yan, Cherian, Joseph, Liu, Boping, Ng, Hui Qi, Lee, Michelle Yueqi, Binte Ahmad, Nur Huda, Poh, Zhi Ying, Wong, Yun Xuan, Huang, Qiwei, Wong, Ying Lei, Hung, Alvin W., Hill, Jeffrey

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 2.48 MB

english, 2015

5

Structure of the transmembrane domain of human nicastrin-a component of γ-secretase

Li, Yan, Liew, Lynette Sin Yee, Li, Qingxin, Kang, CongBao

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.59 MB

english, 2016

6

Structural Insights into the Inhibition of Zika Virus NS2B-NS3 Protease by a Small-Molecule Inhibitor

Li, Yan, Zhang, Zhenzhen, Phoo, Wint Wint, Loh, Ying Ru, Li, Rong, Yang, Hai Yan, Jansson, Anna E., Hill, Jeffrey, Keller, Thomas H., Nacro, Kassoum, Luo, Dahai, Kang, CongBao

Journal:

Year:

2018

Language:

english

File:

PDF, 3.33 MB

english, 2018

7

Secondary structure and membrane topology of dengue virus NS4B N-terminal 125 amino acids

Li, Yan, Kim, Young Mee, Zou, Jing, Wang, Qing-Yin, Gayen, Shovanlal, Wong, Ying Lei, Lee, Le Tian, Xie, Xuping, Huang, Qiwei, Lescar, Julien, Shi, Pei-Yong, Kang, CongBao

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2015

Language:

english

File:

PDF, 1.99 MB

english, 2015

8

Elucidating the bactericidal mechanism of action of the linear antimicrobial tetrapeptide BRBR-NH 2

Lau, Qiu Ying, Li, Jianguo, Sani, Marc-Antoine, Sinha, Sheetal, Li, Yan, Ng, Fui Mee, Kang, CongBao, Bhattacharjya, Surajit, Separovic, Frances, Verma, Chandra, Chia, Cheng San Brian

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2018

Language:

english

File:

PDF, 8.37 MB

english, 2018

9

Identification of covalent active site inhibitors of dengue virus protease

Koh-Stenta, Xiaoying, Joy, Joma, Wang, Si Fang, Kwek, Perlyn, Wee, John, Wan, Kah Fei, Gayen, Shovanlal, Chen, Angela, Kang, CongBao, Lee, May Ann, Poulsen, Anders, Vasudevan, Subhash, Hill, Jeffrey,

Journal:

Drug Design Development and Therapy

Year:

2015

Language:

english

File:

PDF, 3.01 MB

english, 2015

10

Preparation, Functional Characterization, and NMR Studies of Human KCNE1, a Voltage-Gated Potassium Channel Accessory Subunit Associated with Deafness and Long QT Syndrome †,‡

Tian, Changlin, Vanoye, Carlos G., Kang, Congbao, Welch, Richard C., Kim, Hak Jun, George,, Alfred L., Sanders, Charles R.

Journal:

Year:

2007

Language:

english

File:

PDF, 542 KB

english, 2007

11

Biomimetic membrane platform containing hERG potassium channel and its application to drug screening

Arslan Yildiz, Ahu, Kang, CongBao, Sinner, Eva-Kathrin

Journal:

The Analyst (Royal Society of Chemistry)

Year:

2013

Language:

english

File:

PDF, 1.07 MB

english, 2013

12

Characterization of the Molecular Interactions between ParE/Gyrb and an Inhibitor and its Insight into Developing Antibacterial Agents

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 42 KB

english, 2016

13

Solid-Phase Synthesis and NMR Structural Studies of the Marine Antibacterial Cyclic Tetrapeptide: Cyclo[GSPE]

Huichang Annie Lim, CongBao Kang, Cheng San Brian Chia

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2010

Language:

english

File:

PDF, 400 KB

english, 2010

14

Solution structure of the transmembrane domain of the insulin receptor in detergent micelles

Li, Qingxin, Wong, Ying Lei, Kang, CongBao

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2014

Language:

english

File:

PDF, 1.38 MB

english, 2014

15

Lyso-myristoyl phosphatidylcholine micelles sustain the activity of Dengue non-structural (NS) protein 3 protease domain fused with the full-length NS2B

Huang, Qiwei, Li, Qingxin, Joy, Joma, Chen, Angela Shuyi, Ruiz-Carrillo, David, Hill, Jeffrey, Lescar, Julien, Kang, Congbao

Journal:

Protein Expression and Purification

Year:

2013

Language:

english

File:

PDF, 1.37 MB

english, 2013

16

Selection of suitable detergents for obtaining an active dengue protease in its natural form from E. coli

Liew, Lynette Sin Yee, Lee, Michelle Yueqi, Wong, Ying Lei, Cheng, Jinting, Li, Qingxin, Kang, CongBao

Journal:

Protein Expression and Purification

Year:

2016

Language:

english

File:

PDF, 1.88 MB

english, 2016

17

Solution structure of the transmembrane domain of the mouse erythropoietin receptor in detergent micelles

Li, Qingxin, Lei Wong, Ying, Yueqi Lee, Michelle, Li, Yan, Kang, CongBao

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 1.50 MB

english, 2015

18

Structural Studies on the Conformation of Human KCNEL1 Membrane Protein via Electron Paramagnetic Resonance Spectroscopy

Sahu, Indra D., Coey, Aaron T., Troxel, Kaylee R., Gunasekera, Thusitha S., Hawn, Jaclyn M., McCarrick, Robert M., Kang, Congbao, Welch, Richard, Vanoye, Carlos G., Sanders, Charles R., Lorigan, Gary

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 36 KB

english, 2011

19

1H,13C and15N chemical shift assignments for the cyclic-nucleotide binding homology domain of a KCNH channel

Li, Qingxin, Ng, Hui Qi, Kang, CongBao

Journal:

Biomolecular NMR Assignments

Year:

2015

Language:

english

File:

PDF, 394 KB

english, 2015

20

Solution structure of the cyclic-nucleotide binding homology domain of a KCNH channel

Li, Qingxin, Ng, Hui Qi, Yoon, Ho Sup, Kang, Congbao

Journal:

Journal of Structural Biology

Year:

2014

Language:

english

File:

PDF, 2.12 MB

english, 2014

21

The Structural, Dynamic, and Functional Changes in the KCNE1 Membrane Protein Between Detergent Micelles and Lipid Bilayers

Coey, Aaron T., Sahu, Indra D., Troxel, Kaylee R., Gunasekera, Thusitha S., Kang, Congbao, Welch, Richard, Vanoye, Carlos G., Lorigan, Gary A.

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 36 KB

english, 2011

22

Expression, purification, and initial structural characterization of nonstructural protein 2B, an integral membrane protein of Dengue-2 virus, in detergent micelles

Qiwei Huang, Angela Shuyi Chen, Qingxin Li, CongBao Kang

Journal:

Protein Expression and Purification

Year:

2011

Language:

english

File:

PDF, 736 KB

english, 2011

23

Structural transition in Bcl-xL and its potential association with mitochondrial calcium ion transport

Rajan, Sreekanth, Choi, Minjoo, Nguyen, Quoc Toan, Ye, Hong, Liu, Wei, Toh, Hui Ting, Kang, CongBao, Kamariah, Neelagandan, Li, Chi, Huang, Huiya, White, Carl, Baek, Kwanghee, Grüber, Gerhard, Yoon, H

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 1.90 MB

english, 2015

24

Purification and structural characterization of the voltage-sensor domain of the hERG potassium channel

Ng, Hui Qi, Kim, Young Mee, Huang, Qiwei, Gayen, Shovanlal, Yildiz, Ahu Arslan, Yoon, Ho Sup, Sinner, Eva-Kathrin, Kang, CongBao

Journal:

Protein Expression and Purification

Year:

2012

Language:

english

File:

PDF, 738 KB

english, 2012

25

Functional Delivery of a Membrane Protein into Oocyte Membranes Using Bicelles

Kang, Congbao, Vanoye, Carlos G., Welch, Richard C., Van Horn, Wade D., Sanders, Charles R.

Journal:

Year:

2010

Language:

english

File:

PDF, 959 KB

english, 2010

26

Structural Insight into the Transmembrane Domain and the Juxtamembrane Region of the Erythropoietin Receptor in Micelles

Li, Qingxin, Wong, Ying Lei, Huang, Qiwei, Kang, CongBao

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 2.62 MB

english, 2014

27

NMR structural characterization of the N-terminal active domain of the gyrase B subunit from Pseudomonas aeruginosa and its complex with an inhibitor

Li, Yan, Wong, Yun Xuan, Poh, Zhi Ying, Wong, Ying Lei, Lee, Michelle Yueqi, Ng, Hui Qi, Liu, Boping, Hung, Alvin W., Cherian, Joseph, Hill, Jeffrey, Keller, Thomas H., Kang, CongBao

Journal:

Year:

2015

Language:

english

File:

PDF, 2.93 MB

english, 2015

28

Application of microbial enhanced oil recovery technique to Daqing Oilfield

Qingxin Li, Congbao Kang, Hao Wang, Chunde Liu, Changkai Zhang

Journal:

Biochemical Engineering Journal

Year:

2002

Language:

english

File:

PDF, 35 KB

english, 2002

29

Probing the Structural and Dynamic Properties of KCNE1 using Site-Directed Spin Labeling EPR Spectroscopy

Troxel, Kaylee R., Sahu, Indra D., Coey, Aaron T., Swartz, Max S., Hawn, Jaclyn M., Gunasekera, Thusitha S., McCarrick, Robert M., Welch, Richard C., Vanoye, Carlos G., Kang, Congbao, Sanders, Charles

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 40 KB

english, 2012

30

NMR Structural Study of the Domains of the KCNH Channels and its Insight into Channel Gating

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 45 KB

english, 2014

31

Backbone assignment of the N-terminal 24-kDa fragment ofEscherichia colitopoisomerase IV ParE subunit

Li, Yan, Wong, Ying Lei, Lee, Michelle Yueqi, Ng, Hui Qi, Kang, CongBao

Journal:

Biomolecular NMR Assignments

Year:

2016

Language:

english

File:

PDF, 1.16 MB

english, 2016

32

Secondary structure and membrane topology of dengue virus NS4A protein in micelles

Li, Yan, Lee, Michelle Yueqi, Loh, Ying Ru, Kang, CongBao

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2017

Language:

english

File:

PDF, 1.75 MB

english, 2017

33

The Natively Disordered Loop of Bcl-2 Undergoes Phosphorylation-Dependent Conformational Change and Interacts with Pin1

Kang, CongBao, Bharatham, Nagakumar, Chia, Joel, Mu, Yuguang, Baek, Kwanghee, Yoon, Ho Sup, Uversky, Vladimir N.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.60 MB

english, 2012

34

Zika Virus Protease: An Antiviral Drug Target

Kang, CongBao, Keller, Thomas H., Luo, Dahai

Journal:

Trends in Microbiology

Year:

2017

Language:

english

File:

PDF, 3.33 MB

english, 2017

35

NMR solution structure of the N-terminal domain of hERG and its interaction with the S4–S5 linker

Qingxin Li, Shovanlal Gayen, Angela Shuyi Chen, Qiwei Huang, Manfred Raida, CongBao Kang

Journal:

Biochemical and Biophysical Research Communications

Year:

2010

Language:

english

File:

PDF, 1.02 MB

english, 2010

36

EPR Spectroscopic Distance Measurements of the KCNE1 Membrane Protein in Micelles and Lipid Bilayers

Sahu, Indra D., Coey, Aaron T., Troxel, Kaylee R., Gunasekera, Thusitha S., Hawn, Jaclyn M., Swartz, Max S., Smith, Hubbel J., Zhang, Rongfu, McCarrick, Robert M., Kang, Congbao, Welch, Rechard, Vanoy

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 40 KB

english, 2012

37

Structural insight into the transmembrane segments 3 and 4 of the hERG potassium channel

Li, Qingxin, Wong, Ying Lei, Ng, Hui Qi, Gayen, Shovanlal, Kang, CongBao

Journal:

Journal of Peptide Science

Year:

2014

Language:

english

File:

PDF, 2.01 MB

english, 2014

38

Targeting the Central Pocket in Human Transcription Factor TEAD as a Potential Cancer Therapeutic Strategy

Pobbati, Ajaybabu V., Han, Xiao, Hung, Alvin W., Weiguang, Seetoh, Huda, Nur, Chen, Guo-Ying, Kang, CongBao, Chia, Cheng San Brian, Luo, Xuelian, Hong, Wanjin, Poulsen, Anders

Journal:

Year:

2015

Language:

english

File:

PDF, 2.57 MB

english, 2015

39

Characterization of molecular interactions between Zika virus protease and peptides derived from the C-terminus of NS2B

Li, Yan, Loh, Ying Ru, Hung, Alvin W., Kang, CongBao

Journal:

Biochemical and Biophysical Research Communications

Year:

2018

Language:

english

File:

PDF, 1.70 MB

english, 2018

40

EPR Spectroscopic Studies on the Structural and Dynamic Properties of Human KCNE1 Membrane Protein in Lipid Bilayers

Gunasekera, Thusitha S., Coey, Aaron T., Kang, Congbao, Welch, Richard, Vanoye, Carlos G., Sanders, Charles R., Lorigan, Gary A.

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 64 KB

english, 2010

41

Structural analysis of the S4–S5 linker of the human KCNQ1 potassium channel

Gayen, Shovanlal, Li, Qingxin, Kang, CongBao

Journal:

Biochemical and Biophysical Research Communications

Year:

2015

Language:

english

File:

PDF, 1.48 MB

english, 2015

42

Membrane topology of NS2B of dengue virus revealed by NMR spectroscopy

Li, Yan, Li, Qingxin, Wong, Ying Lei, Liew, Lynette Sin Yee, Kang, CongBao

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2015

Language:

english

File:

PDF, 2.58 MB

english, 2015

43

Expression, purification of Zika virus membrane protein-NS2B in detergent micelles for NMR studies

Ng, Elizabeth Yihui, Loh, Ying Ru, Li, Yan, Li, Qingxin, Kang, CongBao

Journal:

Protein Expression and Purification

Year:

2019

Language:

english

File:

PDF, 6.13 MB

english, 2019

44

Progress in Developing Inhibitors of SARS-CoV-2 3C-Like Protease

Li, Qingxin, Kang, CongBao

Journal:

Year:

2020

File:

PDF, 1.70 MB

2020

45

NMR structural study of the intracellular loop 3 of the serotonin 5-HT1A receptor and its interaction with calmodulin

Angela Shuyi Chen, Young Mee Kim, Shovanlal Gayen, Qiwei Huang, Manfred Raida, CongBao Kang

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2011

Language:

english

File:

PDF, 2.13 MB

english, 2011

46

Mechanistic insights into non-immunosuppressive immunophilin ligands as potential antimalarial therapeutics

Ho Sup Yoon, Reema Alag, Congbao Kang, Hong Ye, Masayo Kotaka…

Journal:

Malaria Journal

Year:

2010

Language:

english

File:

PDF, 395 KB

english, 2010

47

Structural characterization of the linked NS2B-NS3 protease of Zika virus

Li, Yan, Phoo, Wint Wint, Loh, Ying Ru, Zhang, Zhenzhen, Ng, Elizabeth Yihui, Wang, Weiling, Keller, Thomas H., Luo, Dahai, Kang, CongBao

Journal:

Year:

2017

Language:

english

File:

PDF, 1.35 MB

english, 2017

48

Secondary Structure and Topology of the Transmembrane Domain of Syndecan-2 in Detergent Micelles

Li, Qingxin, Ng, Hui Qi, Kang, CongBao

Journal:

Year:

2019

Language:

english

File:

PDF, 1.01 MB

english, 2019

49

A Practical Perspective on the Roles of Solution NMR Spectroscopy in Drug Discovery

Li, Qingxin, Kang, CongBao

Journal:

Year:

2020

File:

PDF, 3.56 MB

2020

50

Solution NMR study of integral membrane proteins

CongBao Kang, Qingxin Li

Journal:

Current Opinion in Chemical Biology

Year:

2011

Language:

english

File:

PDF, 1.04 MB

english, 2011

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